The EBMEDS module can be integrated into any electronic health record system (EHR) capable of providing structured patient data. The EHR sends patient data as an XML, JSON or FHIR message to the EBMEDS module. The module analyzes the data and returns a response containing the decision support information in the same format it was sent or in preformatted HTML. The EHR vendor, in collaboration with Duodecim, designs the user interface, in which the decision support information is shown in the EHR workstation.

Decision support rules can be created and edited with a web-based editor, which is available for all end users. The editor works against a database, from which the production package for the EHR is compiled.